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Hou et al (2005) studied the autonomic outcomes of modafinil in human beings. They observed that modafinil affects the locus coeruleus, which mediates pupil diameter and arousal, but it does not affect other autonomic functions, which might be managed by noreadrenergic Command centers (A1 – A5) Found outside of the locus coeruleus.carbamazepine w

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